Molecular shape is calculated using ab-initio methods to fit the protein envelope. This is the fastest route to protein structure in solution.

With full robotic solution handling and delivery, the BioXolver can be set up with multiple samples, dilutions, buffers and automated to run over days.

Sample volumes as small as 5uL can be delivered robotically and kept in the scattering volume by our proprietary optical feedback. Concurrent UV/Vis measures concentration in-situ and an optional in-line Size Exclusion Chromatography (SEC-SAXS) isolates the pure protein scattering from aggregates to ensure a precise measurement and subsequent shape function.